Regenerative Medicine Utrecht

Vacancies

Post-Doc Position: Mesenchymal stem cells and their secretome in the repair of intestinal tissue in Graft versus Host Disease

Profile

We are looking for an enthusiastic, highly motivated candidate with a strong interest in a molecular understanding of biology. We are especially interested in applicants that are excited to work in a collaborative and multidisciplinary environment and have solid background in cell and molecular biology.

Project

The project aims to characterize the molecular mechanisms underlying the regenerative properties of MSC and their secretome in the repair of intestinal tissue in context of therapeutic use of MSC for Graft versus Host Disease.

You will be working with the variety of techniques including: 3D organoid culture, co-culture, Western blotting, flow cytometry, confocal microscopy, differential centrifugation and sucrose gradient, nanoparticle tracking analysis, cutting edge cloning techniques, lentiviral transductions, making transgenic cell lines, 3D organoid culture, co-culture, siRNA knock down and Crispr-Cas9 technology. The project will also make use of the unique material from GvHD patients.

Organization

You will be working at the Regenerative Medicine Center in Utrecht, which offers an international, very dynamic and stimulating work environment. The RMCU is an inter-faculty initiative with scientists from medicine and veterinary medicine gathered together. This provides a unique collaborative setting for regenerative medicine projects. The RMCU houses the world-class equipment and is located in the scientific campus of the Utrecht University with the access to a large number of facilities. Utrecht is beautiful city located in the center of the Netherlands, in close proximity of Amsterdam and its international airport.

Application deadline: 15 August 2019

Application process: Please send one PDF document containing a cover letter with your motivations, a very concise summary of previous research activities, the curriculum vitae and the contact details for 3 referees to m.j.lorenowicz@umcutrecht.nl

Further information: For more information on the research focus of the group please check our website: https://www.msc-biology-group.com. For questions about the position, please send an email to m.j.lorenowicz@umcutrecht.nl.