We focus on advanced heart failure and associated complications, including kidney disease and failing blood vessels.
The most common cause of death, world-wide, is heart disease, which accounts for 31% of all deaths. Heart disease is caused by a loss of cardiomyocytes, usually because of a heart attack or progressing heart failure. Despite advances in how we manage heart disease (lifestyle, medication, interventions), heart disease is progressive, and there is an obvious need to do more than just manage symptoms.
There is no cure for kidney disease. Chronic kidney disease is a serious health care problem that is becoming more prevalent, as growing numbers of patients suffer from diabetes, obesity and arteriosclerosis. Current therapies include controlling symptoms and reducing complications. For patients with end-stage kidney disease, dialysis and transplantation are the only options, and both are not without significant drawbacks.